There may sometimes be minor differences in body asymmetry that vary from person to person. For example, the left hand opening may be one centimeter longer, while the right earlobe may appear a little more drooping when viewed in a mirror. Or asymmetrical changes, such as one breast being larger than the other, may be found in some people. All these differences, as exemplified, are mostly normal and usually nothing to worry about. But sometimes exaggerated physical differences can be significant, even if benign. Some women with breasts of different sizes are uncomfortable with this appearance and want to have plastic surgery to make their appearance more symmetrical. In fact, differences in the size of parts of the body, such as the hands or some limbs (arms and legs), can be so significant that they may be a sign of a more serious illness. This article contains information on the differences seen in some limbs and their causes.
Intrauterine Growth Retardation and Developmental Instability
Intrauterine growth restriction (IUGR) affects about five percent of the obstetric population and is the second leading cause of death and disease in unborn babies following prematurity. The term IUGR is a pathological term for small for gestational age (SGA) and can be symmetrical or asymmetrical. It should be noted that many SGA babies are normal but structurally small. IUGR refers to the SGA that represents the disease or disease. Asymmetric IUGR is usually caused by placental insufficiency where the baby is not getting enough oxygen and nutrition through the placenta. This impaired placental blood flow can be due to many things such as smoking, alcohol, drugs, medications, high blood pressure, and genetic disorders.
A fetus with asymmetric IUGR tries to develop best with the blood given. Head circumference is protected by directing healthy blood flow to organs. However, due to a smaller liver size, the abdominal circumference is reduced, the limbs are skinny and the skin is thin because there is less fat. At birth, scrawny limbs with reduced muscle mass may appear asymmetrical. Asymmetrical IUGR does not mean that mirrored body parts such as limbs differ in size, but that could be a consequence. Rather, it means that the growth pattern is asymmetrical and most energy is directed to vital organs such as the brain and heart.
Symmetrical IUGR causes impairment in the development of even the fetal organs such as heart and brain, when the placental blood flow is impaired or later impaired by the fetus. may result in uniform growth restriction. This improvement is evidenced by the decrease in head circumference, which is a serious complication. It is possible that the IUGR represents the clinical endpoint of developmental instability. The mutation involves minor risks where physiological or radiation stress can change the genetics or appearance of a fetus to a lesser extent, as developmental imbalances or disorders in the womb. However, these changes are noticeable, although they are small. For example, differences can be seen in paired organs such as ears, hands and breasts. These small differences may not result in any barriers, but may be noticeable or alarming for those born with them. In other words, if the uterine environment is even slightly disturbed, it is possible that this discomfort or developmental imbalance can cause minor differences in hand, foot, and breast size.
Why Is One Breast Is Bigger Than Another?
Many women have breast asymmetry. It is common for breasts to be of different volume or shape. Also, an excess of breast tissue (supernumerary breast) can develop in a breast.
Although asymmetrical breasts are the most common normal finding, there are aesthetic treatment options, especially in young women where malignancy is rare. While there is some research on the use of breast surgery to correct breast asymmetry in adolescent girls, it is best for a woman to finish her development and move from adolescence to adulthood before undergoing elective breast surgery. As a result, adolescence is a period of change and breast asymmetries can develop and disappear in this development. In other words, there is no need for surgery when the problem resolves itself. Surgical options to correct breast asymmetry include breast lift, breast reduction and breast augmentation. In addition, lipofilling has come to the fore as an aesthetic and reconstructive procedure in recent years. With lipofilling, fat or autologous fat taken from a woman’s own body is taken, processed and instilled into the breast. When looking at the history of Lipofilling, the American Plastics and Reconstructive Association first published a publication in 1987 stating a recommendation against this procedure. Concerns have been expressed that this procedure may interfere with scarring and breast screening.
Over time, experts have realized that such concerns about scarring due to lipofilation are unfounded and this procedure does not leave more (and possibly much less) scarring than other surgeries such as breast reduction. In 2009, the American Association of Plastic Surgeons reversed its position on lipofilling. Although irregular breasts are a common and normal finding, there has been some retrospective research linking different breast volumes with breast cancer. However, such associations need to be supported by further studies.
Why Is One Hand Bigger Than Another?
Some people have different sized hands and one hand is larger than the other. When viewed separately, each hand may appear in normal proportion. Although rare, possible pathological causes of this phenomenon include hemihypertrophy (hemihipplasia) or local gigantism. Hemihypertrophy can affect not only the hand but also the entire limb (arm or leg). Local gigantism usually occurs due to various genetic or acquired etiologies, one of which may be an arteriovenous fistula of the upper limb. Hemihypertrophy can also be seen as a number of signs in rare genetic syndromes or in condition groups such as Beckwith-Wiedemman syndrome and Proteus syndrome. Hemihypertrophy can also occur with neurofibromatosis type 1. These syndromes are complex and managed by pediatricians, geneticists, and orthopedic surgeons. Importantly, the presence of associated tumors should be ruled out.
A size difference as small as five percent may be helpful in diagnosing hemihypertrophy. However, parents often seek medical attention when differences are greater. On a related note, muscle imbalances can also cause asymmetry in the limbs. For example, if a person tends to work one side of the body more than the other, this can cause significant muscle imbalances in the arm or leg muscle groups. Muscle imbalances are not pathological per se, but a physiological response to the environment.
As a result; many people have different sizes of hands, feet, arms, and breasts. The causes of minimal asymmetries are usually purely benign and newer than the related one. More rarely, greater differences in certain body parts may point to truly identifiable conditions that require diagnosis and treatment by a doctor.